Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TP53 All Species: 13.03
Human Site: S314 Identified Species: 35.83
UniProt: P04637 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P04637 NP_000537.3 393 43653 S314 A L P N N T S S S P Q P K K K
Chimpanzee Pan troglodytes XP_511957 405 44926 S326 A L P N N T S S S P Q P K K K
Rhesus Macaque Macaca mulatta P56424 393 43637 S314 A L P N N T S S S P Q P K K K
Dog Lupus familis XP_861368 586 65737 V384 S M N K L P S V S Q L I N P Q
Cat Felis silvestris
Mouse Mus musculus P02340 387 43137 A308 A L P T C T S A S P P Q K K K
Rat Rattus norvegicus P10361 391 43433 S312 A L P T S T S S S P Q Q K K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P10360 367 40151 E297 S P P T E A P E P P K K R V L
Frog Xenopus laevis P07193 363 40674 E301 V V V D D D E E I F T L R I K
Zebra Danio Brachydanio rerio P79734 373 41881 V308 E E I F T L Q V R G R E R Y E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97 95.6 29.1 N.A. 77.6 77.8 N.A. N.A. 54.2 51.4 51.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97 97.1 44 N.A. 83.2 83.9 N.A. N.A. 67.1 65.3 63.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 13.3 N.A. 66.6 80 N.A. N.A. 13.3 6.6 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 33.3 N.A. 73.3 86.6 N.A. N.A. 33.3 33.3 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 56 0 0 0 0 12 0 12 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 12 12 12 0 0 0 0 0 0 0 0 0 % D
% Glu: 12 12 0 0 12 0 12 23 0 0 0 12 0 0 12 % E
% Phe: 0 0 0 12 0 0 0 0 0 12 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 12 0 0 0 0 0 12 0 0 12 0 12 0 % I
% Lys: 0 0 0 12 0 0 0 0 0 0 12 12 56 56 67 % K
% Leu: 0 56 0 0 12 12 0 0 0 0 12 12 0 0 12 % L
% Met: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 12 34 34 0 0 0 0 0 0 0 12 0 0 % N
% Pro: 0 12 67 0 0 12 12 0 12 67 12 34 0 12 0 % P
% Gln: 0 0 0 0 0 0 12 0 0 12 45 23 0 0 12 % Q
% Arg: 0 0 0 0 0 0 0 0 12 0 12 0 34 0 0 % R
% Ser: 23 0 0 0 12 0 67 45 67 0 0 0 0 0 0 % S
% Thr: 0 0 0 34 12 56 0 0 0 0 12 0 0 0 0 % T
% Val: 12 12 12 0 0 0 0 23 0 0 0 0 0 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _